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Información nutricional
Estudios sobre Ingredientes Activos
Azafrán (Crocus sativus)
- Kashani, L., et al. (2018). "Saffron for treatment of fluoxetine-induced sexual dysfunction in women: randomized double-blind placebo-controlled study." Human Psychopharmacology: Clinical and Experimental, 28(1), 54-60.
- Modabbernia, A., et al. (2014). "Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial." Psychopharmacology, 223(4), 381-388.
- Lopresti, A.L., Drummond, P.D. (2014). "Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action." Human Psychopharmacology, 29(6), 517-527.
Lúpulo y 8-Prenilnaringenina (8-PN)
- Aghamiri, V., et al. (2016). "The effect of Hop (Humulus lupulus L.) on early menopausal symptoms and hot flashes: A randomized placebo-controlled trial." Complementary Therapies in Clinical Practice, 23, 130-135.
- Erkkola, R., et al. (2010). "A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts." Phytomedicine, 17(6), 389-396.
- Possemiers, S., et al. (2005). "Activation of proestrogens from hops (Humulus lupulus L.) by intestinal microbiota; conversion of isoxanthohumol into 8-prenylnaringenin." Journal of Agricultural and Food Chemistry, 53(16), 6281-6288.
L-Teanina
- Hidese, S., et al. (2019). "Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study." Acta Neuropsychiatrica, 29(2), 72-79.
- Williams, J.L., et al. (2016). "The effects of green tea amino acid L-theanine consumption on the ability to manage stress and anxiety levels: a systematic review." Plant Foods for Human Nutrition, 71(1), 12-23.
- Rao, T.P., et al. (2015). "In Search of a Safe Natural Sleep Aid." Journal of the American College of Nutrition, 34(5), 436-447.
- Unno, K., et al. (2013). "Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress." Pharmacology Biochemistry and Behavior, 111, 128-135.
Melatonina
- Comisión Europea. (2012). Reglamento (UE) No 432/2012 por el que se establece una lista de declaraciones autorizadas de propiedades saludables de los alimentos distintas de las relativas a la reducción del riesgo de enfermedad.
- European Food Safety Authority (EFSA). (2010). "Scientific Opinion on the substantiation of health claims related to melatonin." EFSA Journal, 8(2), 1467.
- Ferracioli-Oda, E., et al. (2013). "Meta-analysis: melatonin for the treatment of primary sleep disorders." PLoS ONE, 8(5), e63773.
Vitamina B6
- European Food Safety Authority (EFSA). (2009). "Scientific Opinion on the substantiation of health claims related to vitamin B6." EFSA Journal, 7(9), 1225.
- Wyatt, K.M., et al. (1999). "Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: systematic review." BMJ, 318(7195), 1375-1381.
Magnesio
- Abbasi, B., et al. (2012). "The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial." Journal of Research in Medical Sciences, 17(12), 1161-1169.
- European Food Safety Authority (EFSA). (2010). "Scientific Opinion on the substantiation of health claims related to magnesium." EFSA Journal, 8(10), 1807.
Vitaminas D3 y K2
- Knapen, M.H., et al. (2013). "Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women." Osteoporosis International, 24(9), 2499-2507.
- Iwamoto, J., et al. (2009). "Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis." Journal of Orthopedic Science, 5(6), 546-551.
- European Food Safety Authority (EFSA). (2009). "Scientific Opinion on the substantiation of health claims related to vitamin D." EFSA Journal, 7(9), 1227.
Normativa Europea y Regulaciones
- Reglamento (CE) No 1924/2006 del Parlamento Europeo y del Consejo, relativo a las declaraciones nutricionales y de propiedades saludables en los alimentos.
- Agencia Española de Seguridad Alimentaria y Nutrición (AESAN). Complementos Alimenticios. Disponible en: https://www.aesan.gob.es
- European Commission. EU Register of nutrition and health claims made on foods. Disponible en: https://ec.europa.eu/food/safety/labelling_nutrition/claims/register/public/
Estudios sobre Menopausia y Salud Femenina
- Nelson, H.D. (2008). "Menopause." The Lancet, 371(9614), 760-770.
- Baber, R.J., et al. (2016). "2016 IMS Recommendations on women's midlife health and menopause hormone therapy." Climacteric, 19(2), 109-150.
- Freeman, E.W., et al. (2014). "Symptoms associated with menopausal transition and reproductive hormones in midlife women." Obstetrics & Gynecology, 123(4), 753-760.
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